Posts from: May 2013
A research team from the University of Twente has found a way to obtain high resolution images of a fluorescent object through a strongly scattering medium. This has been a goal of bioimaging scientists for some time, as it would allow us to use visible light to image much deeper into tissue. Various methods have been suggested, but they generally need some kind of ‘guide-star’ behind the scattering layer. The new approach uses the ‘memory effect’ of speckle to avoid the need for any calibration or guide-star, potentially making it much more applicable to real situations.
Researchers at the University of Maryland have developed a low-cost fibre sensor for detecting blood flow. It has a diameter of just 125 microns, meaning it could be incorporated into a surgical instrument to alert the operator that they are approaching a blood vessel. It combines features of laser Doppler flowmetry and low coherence interferometry to provide a measurement with high spatial localisation, but without many of the complications of a full Doppler optical coherence tomography (OCT) system.