Posts from: February 2013

High Resolution Fluorescence Endomicroscopy Using a Multi-mode Fibre

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I recently discussed a paper by a group from Korea University,Seoul, who had developed a reflection-mode widefield endomicroscope using a multi-mode fibre. Other people have been thinking along the same lines, including a Swiss group who have recently published details of another multi-mode fibre based device. Unlike the widefield implementation, this method uses digital phase conjugation to scan a point of light at the far-end of the fibre, making fluorescence imaging possible. The basic idea isn’t new, but the group was able to demonstrate better resolution than previous reports through the use of a very high NA, double clad fibre.
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